Alpha 1-Antitrypsin Phenotype

Pathology category

Biochemistry - referred tests

Code

AATP

Referral code

Request form

Test information

Sent if quantitative a1AT is less than 1.3 g/l and on all paediatric AATs. May be requested in the investigation of liver disease in neonates/infants with A1AT of any value. May be requested in the investigation of recurrent lung infections in all ages. If requested in neonates – must be 3-4 weeks post transfusion for phenotyping.

Guidelines

Pre-analytical

May be raised in acute phase response

Reference range

see report

Tube type

Tube type info

SST

Special requirements

Serum

Minimum volume

2 mL

Assay frequency

TAT Inpatient (urgent)

TAT Inpatient

3 weeks

TAT GP/Outpatient

3 weeks

Referral lab

Protein Reference Unit & Immunology, Sheffield Teaching Hospitals