Caeruloplasmin

Pathology category

Biochemistry

Code

CAER

Referral code

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Test information

A copper transport protein. Caeruloplasmin is useful in conjunction with plasma and urinary copper in the diagnosis of Wilsons disease. Caeruloplasmin is low in patients with severe liver disease irrespective of aetiology. Low values are also seen in malnutrition, malabsorption and nephrotic syndrome. Elevated values are seen in infections, malignancy and trauma. Particularly high values are seen Lymphoma and infection or obstruction of the biliary tract.

Guidelines

Pre-analytical

Reference range

0.20 – 0.60 g/L

Source: Beckman Coulter

Tube type

Tube type info

Adults: 5ml Serum SST (gold top)

Paediatrics: 0.5ml lithium/heparin (orange top)

Special requirements

Minimum volume

Adults: 0.5ml

Paediatrics: 0.3 ml

Assay frequency

Run daily at local laboratory

TAT Inpatient (urgent)

TAT Inpatient

3 days

TAT GP/Outpatient

3 days

Referral lab

Local, Clinical Biochemistry