IGG Subclasses

Pathology category

Immunology

Code

IGSC

Referral code

RHH

Request form

Test information

IgG1 and IgG2 subclass deficiencies are the most clinically important in individuals who suffer recurrent infections. However, functional antibodies to tetanus (requiring the presence of IgG1) and pneumococcus (requiring the presence of IgG2) give a much clearer picture of the patient’s ability to mount an appropriate antibody response and should be used in preference. All requests for IgG Subclasses will be referred to an Immunology Consultant to establish the clinical relevance.

Guidelines

Pre-analytical

Reference range

See: IgG Subclasses | North Bristol NHS Trust (nbt.nhs.uk)

Tube type

Tube type info

SST, Plain or Lithium Heparin

Special requirements

Serum

Minimum volume

Assay frequency

Sent Away to a second Referral Lab. May take a further 2-3 weeks

TAT Inpatient (urgent)

TAT Inpatient

TAT GP/Outpatient

up to 4 weeks

Referral lab

Immunology Russells Hall Hospital