P1NP

Pathology category

Biochemistry - referred tests

Code

P1NP

Referral code

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Test information

Rarely indicated, discuss with biochemist. Procollagen 1 (P1NP) concentrations reflect osteoblast activity so any disease increasing the activity of osteoblasts or activation frequency of the bone forming unit will result in elevated P1NP concentrations. Low P1NP may indicate adynamic bone (for more details see: https://mft.nhs.uk/app/uploads/2020/01/Type-I-Procollagen-N-terminal-Peptide-P1NP.pdf).

Guidelines

Pre-analytical

Reference range

see report

Tube type

Tube type info

Li Hep or SST or red top

Special requirements

Plasma or serum

Minimum volume

Assay frequency

TAT Inpatient (urgent)

TAT Inpatient

4 weeks

TAT GP/Outpatient

4 weeks

Referral lab

Dept of Clinical Biochemistry, Manchester Royal Infirmary