Renin Activity

Pathology category

Biochemistry - referred tests

Code

REN

Referral code

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Test information

Diagnosis of, and differentiation between, primary and secondary causes of hyper or hypoaldosteronism. See CONN (aldosterone and renin) Management of renal artery stenosis. Diagnosis of renin secreting tumours. Monitoring mineralocorticoid replacement therapy in CAH.

Guidelines

Pre-analytical

DO NOT PLACE BLOOD SAMPLE IN FRIDGE OR ON ICE. Sample must be spun within 4hrs ofcollection. Varies with sodium intake, posture, age and is affected by drug treatment.

Reference range

Units: pmol/mL/Hr Random: 0.5 – 3.1; Recumbent overnight: 1.1 – 2.7, Ambulant: 2.8 – 4.5

Tube type

Tube type info

Li Hep (EDTA acceptable)

Special requirements

Plasma

Minimum volume

100 uL

Assay frequency

TAT Inpatient (urgent)

TAT Inpatient

4 weeks

TAT GP/Outpatient

4 weeks

Referral lab

Dept of Clinical Biochemistry, Charing Cross Hospital