Varicella IgG Serology

Varicella IgG Serology image

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Pathology category

Microbiology - Virology

Code

VZG

Referral code

Request form

ICE request form. Requesting Varicella zoster antibodies/Immune status: In order to assess the significance of the result, the context in which the request has been made is important to determine whether further action is required in the event that the patient is non-immune (e.g. administration of acyclovir prophylaxis or VZIG).

Test information

For immunocompetent individuals including pregnant individuals, a history of previous chickenpox, shingles or 2 doses of varicella vaccine is sufficient evidence of immunity. Antibody testing is NOT indicated.

In those without such a history, antibody testing can help to identify those individuals that would benefit from VZ PEP

Please provide the following information with all requests:

If pregnant/immunocompromised:
• Estimated date of delivery
• Nature of immunosuppression (e.g. chemotherapy, HIV, steroids)
• Nature of contact with a case of chickenpox/shingles
– Symptoms and date of onset of rash in contact
– Date(s) of contact
– Nature of contact (e.g. household, social)

If neonate:
• Gestational age at birth
• History of previous chickenpox in mother
• Nature of contact with a case of chickenpox/shingles
– Symptoms and date of onset of rash in contact
– Date(s) of contact
– Nature of contact (e.g. household, social)

Whether routine immunity check e.g. for Occupational Health purposes, or prior to immunosuppressive therapy

Tests performed in a UKAS Accredited Medical Laboratory No. 8873.

Guidelines

Pre-analytical

Please ensure the sample is transported to the laboratory as soon as possible. If delayed please refrigerate.

Reference range

Tube type

5ml gold top clotted SST

Tube type info

5ml gold top clotted SST

Special requirements

Minimum volume

5ml

Assay frequency

Monday – Friday

TAT Inpatient (urgent)

1 - 7 days

TAT Inpatient

1 - 7 days

TAT GP/Outpatient

1 - 7 days

Referral lab